2013
2013-1 Takasawa A, Kojima T, Ninomiya T, Tsujiwaki M, Murata M, Tanaka S, Sawada N. Behavior of tricellulin during destruction and formation of tight junctions under various extracellular calcium conditions. Cell Tissue Res, 351(1): 73-84, 2013.
2013-2 Sawada N. Tight junction-related human diseases. Pathol Int, 63(1): 1-12, 2013.
2013-3 Fuchimoto J, Kojima T, Okabayashi T, Masaki T, Ogasawara N, Obata K, Nomura K, Hirakawa S, Kobayashi N, Shigyo T, Yokota SI, Fujii N, Tsutsumi H, Himi T, Sawada N. Humulone suppresses replication of respiratory syncytial virus and release of IL-8 and RANTES in normal human nasal epithelial cells. Med Mol Morphol, in press.
2013-4 Kyuno D, Kojima T, Yamaguchi H, Ito T, Kimura Y, Imamura M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N. Protein kinase Cα inhibitor protects against downregulation of claudin-1 during epithelial-mesenchymal transition of pancreatic cancer. Carcinogenesis, in press.
2012
2012-1 Inatomi S, Ohguro H, Nishikiori N, Sawada N. Glial cell derived cytokines and vascular integrity in diabetic retinopathy. Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement, edited by Tombran-Tink,J., Barnstable,C.J. and Gardner,T.W., Humana Press, 325-338, 2012.
2012-2 Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T. The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis. Clin Exp Allergy, 42(2): 218-228, 2012.
2012-3 Maeda T, Murata M, Chiba H, Takasawa A, Tanaka S, Kojima T, Masumori N, Tsukamoto T, Sawada N. Claudin-4-targeted therapy using Clostridium perfringens enterotoxin for prostate cancer. Prostate, 72(4): 351-360, 2012.
2012-4 Soini Y, Takasawa A, Eskelinen M, Juvonen P, Kärjä V, Hasegawa T, Murata M, Tanaka S, Kojima T, Sawada N. Expression of claudins 7 and 18 in pancreatic ductal adenocarcinoma: association with features of differentiation. J Clin Pathol, 65(5): 431-436, 2012.
2012-5 Nomura K, Kojima T, Fuchimoto J, Obata K, Keira T, Himi T, Sawada N. Regulation of interleukin-33 and thymic stromal lymphopoietin in human nasal fibroblasts by proinflammatory cytokines. Laryngoscope, 122(6): 1185-1192, 2012.
2012-6 Ara S, Kikuchi T, Matsumiya H, Kojima T, Kubo T, Ye RC, Sato A, Kon SI, Honma T, Asakura K, Hasegawa T, Himi T, Sato N, Ichimiya S. Sorting Nexin 5 of a New Diagnostic Marker of Papillary Thyroid Carcinoma Regulates Caspase-2. Cancer Sci, in press.
2012-7 Hanai K, Kojima T, Ota M, Onodera J, Sawada N. Effects of atelocollagen formulation containing oligonucleotide on endothelial permeability. J Drug Deliv, 2012: 245835, 2012.
2012-8 Ogawa M, Kojima T, Someya M, Nomura K, Takasawa A, Murata M, Tanaka S, Saito T, Sawada N. Epidermal growth factor modulates claudins and tight junctional functions in ovarian cancer cell lines. Histochem Cell Biol, 138(2): 323-338, 2012.
2012-9 Kojima T, Sawada N. Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells. Ann N Y Acad Sci, 1257(1):85-92, 2012.
2012-10 Kojima T, Kyuno D, Sawada N. Targeting claudin-4 in human pancreatic cancer. Expert Opin Ther Targets, 16(9): 881-887, 2012.
2012-11 Tanaka S, Takasawa A, Fukasawa Y, Hasegawa T, Sawada N. An undifferentiated embryonal sarcoma of the liver containing adipophilin-positive vesicles in an adult with massive sinusoidal invasion. Int J Clin Exp Pathol, 5(8): 824-829, 2012.
2012-12 Takasawa A, Kojima T, Ninomiya T, Tsujiwaki M, Murata M, Tanaka S, Sawada N. Behavior of tricellulin during destruction and formation of tight junctions under various extracellular calcium conditions. Cell Tissue Res, in press.
2012-13 Fuchimoto J, Kojima T, Kobayashi N, Ohkuni T, Ogasawara N, Masaki T, Obata K, Nomura K, Kondoh A, Shigyo T, Himi T, Sawada N. Hop water extract inhibits double-stranded RNA-induced thymic stromal lymphopoietin release from human nasal epithelial cells. Am J Rhinol Allergy, 26(6):433-438, 2012.
2011
2011-1 Ohkuni T, Kojima T , Ogasawara N, Masaki T, Fuchimoto J, Kamekura R, Koizumi J, Ichimiya S, Murata M, Tanaka S, Himi T, Sawada N. Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-alpha via distinct NF-kappaB pathways in human nasal epithelial cells. Toxicology and Applied Pharmacology, 250: 29-38, 2011.
2011-2 Ogasawara N, Kojima T, Go M, Takano K, Kamekura R, Ohkuni T, Koizumi J, Masaki T, Fuchimoto J, Obata K, Kurose M, Shintani T, Sawada N, Himi T. Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids. Acta Otolaryngol, 131: 116-123, 2011.
2011-3 Kondoh A, Takano K, Kojima T, Ohkuni T, Kamekura R, Ogasawara N, Go M, Sawada N, Himi T.Altered expression of claudin-1, claudin-7, and tricellulin regardless of human papilloma virus infection in human tonsillar squamous cell carcinoma. Acta-Otolaryngol, 131(8): 861-868, 2011.
2011-4 Masaki T, Kojima T, Okabayashi T, Ogasawara N, Ohkuni T, Obata K, Takasawa A, Murata M, Tanaka S, Hirakawa S, Fuchimoto J, Ninomiya T, Fujii N, Tsutsumi H, Himi T, Sawada N. An NF-kappaB signaling pathway via PKCδ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells. Mol Biol Cell, 22(13): 2144-2156, 2011.
2011-5 Kojima T, Sawada N. Expression and function of claudins in hepatocytes. Methods in Molecular Biology, 762: 233-244, 2011.
2011-6 Ito T, Kojima T, Yamaguchi H, Kyuno D, Kimura Y, Imamura M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N. Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathway and modification of DNA-methylation in human pancreatic cancer cells. J Cell Biochem, 112(7): 1761-1772, 2011.
2011-7 Yamaguchi H, Kojima T, Ito T, Kyuno D, Kimura Y, Imamura M, Hirata K, Sawada N. Effects of Clostridium perfringens enterotoxin via claudin-4 on normal human pancreatic duct epithelial cells and cancer cells. Cell Mol Biol Lett, 16(3): 385-397, 2011.
2011-8 Kojima T, Takasawa A, Kyuno D, Ito T, Yamaguchi H, Hirata K, Tsujiwaki M, Murata M, Tanaka S, Sawada N. Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells. Exp Cell Res, 317(16): 2288-2298, 2011.
2011-9 Okabayashi T, Kojima T, Masaki T, Yokota SI, Imaizumi T, Tsutsumi H, Himi T, Fujii N, Sawada N. Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells. Virus Res, 160(1-2): 360-366, 2011.
2011-10 Ariki S, Kojima T, Gasa S, Saito A, Nishitani C, Takahashi M, Shimizu T, Kurimura Y, Sawada N, Fujii N, Kuroki Y. Pulmonary Collectins Play Distinct Roles in Host Defense against Mycobacterium avium. J Immunol, 187(5): 2586-2594, 2011.
2011-11 Kojima T, Himi T, Tsutsumi H, Sawada N. Tight junctions in upper airway epithelium. Endothelium and Epithelium: Composition, Functions and Pathology. Edited by Carrasco E and Mota M. Nova Science Publishers, 2011.
2011-12 Himi T, Takano K, Ogasawara N, Go M, Kurose M, Koizumi J, Kamekura R, Kondo A, Ohkuni T, Masaki T, Kojima T, Sawada N, Tsutsumi H. Mucosal immune barrier and antigen-presenting system in human nasal epithelial cells. Adv Otorhinolaryngol, 72: 28-30, 2011.
2011-13 Tsutsumi H, Kojima T, Hirakawa S, Masaki T, Okabayashi T, Yokota S, Fujii N, Himi T, Sawada N. Respiratory syncytial virus infection and the tight junctions of nasal epithelial cells. Adv Otorhinolaryngol, 72: 153-156, 2011.
2011-14 Kyuno D, Kojima T, Ito T, Yamaguchi H, Tsujiwaki M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N. Protein kinase C alpha inhibitor enhances the sensitivity of human pancreatic cancer HPAC cells to Clostridium perfringens enterotoxin via claudin-4. Cell Tissue Res, 346(3): 369-381, 2011.
2011-15（1） 小島隆，村田雅樹，高澤啓，田中敏，澤田典均．細胞間結合装置．日本臨床分子形態学会編． 病気の分子形態学．東京，学際企画，54-57, 2011.
2011-15（2） 高野賢一，郷充，亀倉隆太，小島隆．鼻アレルギーとタイト結合．日本臨床分子形態学会編． 病気の分子形態学．東京，学際企画，148-149, 2011.
2010
2010-1 Osanai M, Sawada N, Lee GH. Oncogenic and cell survival properties of the retinoic acid metabolizing enzyme, CYP26A1. Oncogene, 29: 1135-1144, 2010.
2010-2 Osanai M, Nishikiori N, Lee GH, Sawada N. Emerging novel treatment strategies for diabetic eye diseases. Curr Diabetes Rev, 6: 35-41, 2010.
2010-3 Kamekura R, Kojima T, Takashima A, Koizumi JI, Ogasawara N, Go M, Takano KI, Murata M, Tanaka S, Ichimiya S, Himi T, Sawada N. Thymic stromal lymphopoietin induces tight junction protein claudin-7 via NF-kappaB in dendritic cells. Histochem Cell Biol, 133: 339-348, 2010.
2010-4 Sawada K, Ariki S, Kojima T, Saito A, Yamazoe M, Nishitani C, Shimizu T, Takahashi M, Mitsuzawa H, Yokota SI, Sawada N, Fujii N, Takahashi H, Kuroki Y. Pulmonary collectins protect macrophages against pore-forming activity of Legionella pneumophila and suppress its intracellular growth. J Biol Chem, 285: 8434-8443, 2010.
2010-5 Ogasawara N, Kojima T, Go M, Ohkuni T, Koizumi J, Kamekura R, Masaki T, Murata M, Tanaka S, Fuchimoto J, Himi T, Sawada N. PPARgamma agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells. Pharmacol Res, 61: 489-498, 2010.
2010-6 Yamaguchi H, Kojima T, Ito T, Kimura Y, Imamura M, Son S, Koizumi J, Murata M, Nagayama M, Nobuoka T, Tanaka S, Hirata K, Sawada N. Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells. Am J Pathol, 177: 698-712, 2010.
2010-7 Kojima T, Fuchimoto J, Yamaguchi H, Ito T, Takasawa A, Ninomiya T, Kikuchi S, Ogasawara N, Ohkuni T, Masaki T, Hirata K, Himi T, Sawada N. c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells. J Cell Physiol, 225:720-733, 2010.
2010-8 Kikuchi S, Ninomiya T, Tatsumi H, Sawada N, Kojima T. Tricellulin is expressed in autotypic tight junctions of peripheral myelinating Schwann cells. J Histochem Cytochem, 58(12): 1067-1073, 2010.
2010-9 杉本幸太郎，藤田裕樹，稲富周一郎，澤田典均，千葉英樹．タイト結合を介したミネラル輸送調節．腎と骨代謝，23(2): 145-147, 2010.
2010-10 三輪洋人，大島忠之，勝野達郎，澤田典均．細胞間ジャンクションの新たなる展開．Pharma Medica, 28(9): 163-169, 2010.
2010-11 澤田典均. 細胞傷害・変性と細胞死. 鈴木利光, 山川光徳, 吉野正編. ダイナミック病理学‐365症例からのアプローチ‐. 東京, 西村書店, 3-10,2010.
2010-12 堤 裕幸，平川賢史，正木智之，氷見徹夫，岡林環樹，横田伸一，藤井暢弘，小島 隆， 澤田典均. RSウイルス感染症と喘鳴・喘息. 小児耳鼻咽喉科， 31(3):248-252,2010.
2010-13 伊東竜哉，山口洋志，小島 隆，澤田典均，平田公一．消化器癌とタイト結合・クローディン，Surgery Frontier, 17(2):60-63,2010.
2010-14 Kikuchi S, Ninomiya T, Kawamata T, Ogasawara N, Kojima T, Tachi N, Tatsumi H. The acid-sensing ion channel 2 (ASIC2) of ciliated cells in the developing rat nasal septum. Arch Histol Cytol, 73(2): 81-9, 2010.
2009
2009-1 Iba K, Hatakeyama N, Kojima T, Murata M, Matsumura T, Wewer UM, Wada T, Sawada N, Yamashita T. Impaired cutaneous wound healing in mice lacking tetranectin. Wound Repair Regen, 17: 108-112, 2009.
2009-2 Son S, Kojima T, Decaens C, Yamaguchi H, Ito T, Imamura M, Murata M, Tanaka S, Chiba H, Hirata K, Sawada N. Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells. Histochem Cell Biol, 131: 411-424, 2009.
2009-3 Liu H, Koyanagi I, Chiba H, Wanibuchi M, Honmou O, Yamaki T, Houkin K. Spinal cord infarct as the initial clinical presentation of intravascular malignant lymphomatosis. J Clin Neurosci, 16: 570-573, 2009.
2009-4 Kojima T, Murata M, Yamamoto T, Lan M, Imamura M, Son S, Takano K-i, Yamaguchi H, Ito T, Tanaka S, Chiba H, Hirata K, Sawada N. Tight junction proteins and signal transduction pathways in hepatocytes. Histol Histopathol, 24: 1463-1472, 2009.
2009-5 小島隆，村田雅樹，澤田典均．肝癌自然発症マウスでの知見-Cx32欠損マウスを用いて- 日本臨床，67: 105-109, 2009.
2009-6 Kamekura R, Kojima T, Koizumi J, Ogasawara N, Kurose M, Go M, Harimaya A, Murata M, Tanaka S, Chiba H, Himi T, Sawada N. Thymic stromal lymphopoietin enhances tight junction barrier function of human nasal epithelial cells. Cell Tissue Res, 338: 283-293, 2009.
2009-7 氷見徹夫，郷充，近藤敦，高野賢一，正木智之，小泉純一，亀倉隆太，大國毅，小笠原徳子，小島隆，澤田典均．ヒト鼻粘膜の機能解析から見えてくること．耳鼻咽喉科展望，52: 9-18, 2009.
2009-8 Ohkuni T, Kojima T, Ogasawara N, Masaki T, Ninomiya T, Kikuchi S, Go M, Takano K, Himi T, Sawada N. Expression and localization of tricellulin in human nasal epithelial cells in vivo and in vitro. Med Mol Morphol, 42: 204-211, 2009.
2009-9 Ogasawara N, Kojima T, Go M, Fuchimoto J, Kamekura R, Koizumi J, Ohkuni T, Masaki T, Murata M, Tanaka S, Ichimiya S, Himi T, Sawada N. Induction of JAM-A during differentiation of human THP-1 dendritic cells. Biochem Biophys Res Commun, 389: 543-549, 2009.
2009-10 Kojima T, Sawada N, Yamaguchi H, Fort AG, Spray DC. Gap and tight junctions in liver: composition, regulation, and function. The Liver: Biology and Pathobiology, 5th Edition, edited by Arias IM, et al. Lippincott Williams&Wilkins, Philadelphia, pp201-220, 2009.
2008
2008-01 Satake S, Semba S, Matsuda Y, Usami Y, Chiba H, Sawada N, Kasuga M, Yokozaki H. Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma. Pathol Int, 58: 156-163, 2008.
2008-02 Chiba H, Osanai M, Murata M, Kojima T, Sawada N. Transmembrane proteins of tight junctions. BBA–Biomembranes, 1778: 588-600, 2008.
2008-03 Nakayama F, Semba S, Usami Y, Chiba H, Sawada N, Yokozaki H. Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma. Pathobiology, 75: 177-185, 2008.
2008-04 Kamekura R, Kojima T, Koizumi J, Ogasawara N, Kurose M, Takano K, Go M, Himi T, Sawada N. Expression of thymic stromal lymphopoietin (TSLP) in allergic rhinitis : Induction of tight junction proteins in human nasal epithelial cells and dendritic cells by epithelial-derived TSLP. Inflammation and Regeneration, 28: 160-165, 2008.
2008-05 Takano K, Kojima T, Ogasawara N, Go M, Kikuchi S, Ninomiya T, Kurose M, Koizumi J, Kamekura R, Murata M, Tanaka S, Chiba H, Himi T, Sawada N. Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro. J Mol Histol, 39(3): 265-273, 2008.
2008-06 Eijken M, Meijer IM, Westbroek I, Koedam M, Chiba H, Uitterlinden AG, Pols HA, van Leeuwen JP. Wnt signaling acts and is regulated in a human osteoblast differentiation dependent manner. J Cell Biochem, 104: 568-579, 2008.
2008-07 Fujita H, Sugimoto K, Inatomi S, Maeda T, Osanai M, Uchiyama Y, Yamamoto Y, Wada T, Kojima T, Yokozaki H, Yamashita T, Kato S, Sawada N, Chiba H. Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Mol Biol Cell, 19: 1912-1921, 2008.
2008-08 Koizumi J, Kojima T, Ogasawara N, Kamekura R, Kurose M, Go M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N. Protein kinase C enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation. Mol Pharmacol, 74: 432-442, 2008.
2008-09 Nishikiori N, Osanai M, Chiba H, Kojima T, Inatomi S, Ohguro H, Sawada N. Experimental effect of retinoic acids on apoptosis during the development of diabetic retinopathy. Clinical Ophthalmology, 2: 233-235, 2008.
2008-10 Kojima T, Takano K, Yamamoto T, Imamura M, Murata M, Son S, Yamaguchi H, Osanai M, Chiba H, Himi T, Sawada N. Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes. Liver Int, 28: 534-545, 2008.
2008-11 Bruedigam C, Koedam M, Chiba H, Eijken M, van Leeuwen JP. Evidence for multiple peroxisome proliferator-activated receptor gamma transcripts in bone: Fine-tuning by hormonal regulation and mRNA stability. FEBS Lett, 582: 1618-1624, 2008.
2008-12 郷充，小島隆，亀倉隆太，小笠原徳子，小泉純一，黒瀬誠，高野賢一，澤田典均，氷見徹夫．粘膜のバリアと抗原サンプリング-鼻粘膜を介した新たな治療戦略にむけて- 耳鼻咽喉科展望，51: 32-38, 2008.
2008-13 Nishikiori N, Sawada N, Ohguro H. Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9. Jpn J Ophthalmol, 52: 195-203, 2008.
2008-14 Hatakeyama N, Kojima T, Iba K, Murata M, Thi MM, Spray DC, Osanai M, Chiba H, Ishii S, Yamashita T, Sawada N. IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway. Cell Tissue Res, 334: 243-254, 2008.
2008-15 明石祐史. 上皮細胞の接着と極性形成におけるタイト結合膜貫通分子claudin-6の役割. 札幌医学雑誌, 77: T65-T71, 2008.
2007
2007-01 Sakai N, Chiba H, Fujita H, Akashi Y, Osanai M, Kojima T, Sawada N. Expression patterns of claudin family of tight-junction proteins in the mouse prostate. Histochem Cell Biol, 127: 457-462, 2007.
2007-02 Osanai M, Nishikiori N, Murata M, Chiba H, Kojima T, Sawada N. Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis. Mol Pharmacol, 71: 250-258, 2007.
2007-03 Ueda J, Semba S, Chiba H, Sawada N, Seo Y, Kasuga M, Yokozaki H. Heterogeneous expression of claudin-4 in human colorectal cancer: decreased claudin-4 expression at the invasive front correlates cancer invasion and metastasis. Pathobiology, 74: 32-41, 2007.
2007-04 Nishikiori N, Osanai M, Chiba H, Kojima T, Ohguro H, Sawada N. Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains. Invest Ophthalmol Vis Sci, 48: 2224-2229, 2007.
2007-05 Nishikiori N, Osanai M, Chiba H, Kojima T, Mitamura Y, Ohguro H, Sawada N. Glial cell-derived cytokines attenuate the breakdown of vascular integrity in diabetic retinopathy. Diabetes, 56: 1333-1340, 2007.
2007-06 Tokunaga Y, Kojima T, Osanai M, Murata M, Chiba H, Tobioka H, Sawada N. A novel monoclonal antibody against the second extracellular loop of occludin disrupts epithelial cell polarity. J Histochem Cytochem, 55: 735-744, 2007.
2007-07 Imamura M, Kojima T, Lan M, Son S, Murata M, Osanai M, Chiba H, Hirata K, Sawada N. Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions. Exp Cell Res, 313: 1951-1962, 2007.
2007-08 Matsuda Y, Semba S, Ueda J, Fuku T, Hasuo T, Chiba H, Sawada N, Kuroda Y, Yokozaki H. Gastric and intestinal claudin expression at the invasive front of gastric carcinoma. Cancer Sci, 98: 1014-1019, 2007.
2007-09 Osanai M, Murata M, Nishikiori N, Chiba H, Kojima T, Sawada N. Occludin-mediated premature senescence is a fail-safe mechanism against tumorigenesis in breast carcinoma cells. Cancer Sci, 98: 1027-1034, 2007.
2007-10 氷見徹夫，郷充，高野賢一，黒瀬誠，小泉純一，亀倉隆太，小島隆，澤田典均．アレルギー性鼻炎における鼻粘膜上皮バリアと抗原認識・提示機構．臨床免疫・アレルギー科，47(4): 427-433, 2007.
2007-11 Osanai M, Murata M, Chiba H, Kojima T, Sawada N. Epigenetic silencing of claudin-6 promotes anchorage-independent growth of breast carcinoma cells. Cancer Sci, 98: 1557-1562, 2007.
2007-12 Koizumi J, Kojima T, Kamekura R, Kurose M, Harimaya A, Murata M, Osanai M, Chiba H, Himi T, Sawada N. Changes of gap and tight junctions during differentiation of human nasal epithelial cells using primary human nasal epithelial cells and primary human nasal fibroblast cells in a noncontact coculture system. J Membr Biol, 218: 1-7, 2007.
2007-13 Kurose M, Kojima T, Koizumi J, Kamekura R, Ninomiya T, Murata M, Ichimiya S, Osanai M, Chiba H, Himi T, Sawada N. Induction of claudins in passaged hTERT-transfected human nasal epithelial cells with an extended life span. Cell Tissue Res, 330: 63-74, 2007.
2007-14 小島隆，村田雅樹，澤田典均．肝細胞タイト結合，claudinと肝小葉．肝胆膵，55(1): 45-54, 2007．
2007-15 Kojima T, Murata M, Go M, Spray DC, Sawada N. Connexins induce and maintain tight junctions in epithelial cells. J Membr Biol, 217: 13-19, 2007.
2007-16 氷見徹夫, 郷充, 高野賢一, 黒瀬誠, 小泉純一, 亀倉隆太, 小笠原徳子, 小島隆, 澤田典均. アレルギー性鼻炎における鼻粘膜上皮バリアと免疫調節機構. アレルギーの臨床, 7(13): 1038-1043, 2007.
2006
2006-01 Chiba H, Kojima T, Osanai M, Sawada N. The significance of interferon--triggered internalization of tight-junction proteins in inflammatory bowel disease. Sci STKE, 316: pe1, 2006.
2006-02 Delhanty PJ, van der Eerden BC, van der Velde M, Gauna C, Pols HA, Jahr H, Chiba H, van der Lely AJ, van Leeuwen JP. Ghrelin and unacylated-ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1a. J Endocrinol, 188(1): 37-47, 2006.
2006-03 Usami Y, Chiba H, Nakayama F, Ueda J, Matsuda Y, Sawada N, Komori T, Ito A, Yokozaki H. Reduced expression of claudin-7 correlates with invasion and metastasis in squamous cell carcinoma of the esophagus. Hum Pathol, 37: 569-577, 2006.
2006-04 Lan MD, Kojima T, Murata M, Osanai M, Takano K, Chiba H, Sawada N. Phosphorylation of ezrin enhances microvillus length via a p38 MAP-kinase pathway in an immortalized mouse hepatic cell line. Exp Cell Res, 312: 111-120, 2006.
2006-05 Kitajima Y, Endo T, Nagasawa K, Manase K, Honnma H, Baba T, Hayashi T, Chiba H, Sawada N, Saito T. Hyperstimulation and a gonadotropin-releasing hormone agonist modulate ovarian vascular permeability by altering expression of the tight junction protein claudin-5. Endocrinology, 147: 694-699, 2006.
2006-06 Nagasawa K, Chiba H, Fujita H, Kojima T, Saito T, Endo T, Sawada N. Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells. J Cell Physiol, 208: 123-132, 2006.
2006-07 van Driel M, Koedam M, Buurman CJ, Roelse M, Weyts F, Chiba H, Uitterlinden AG, Pols HAP, van Leeuwen JPTM. Evidence that both 1,25-dihydroxyvitamin D3 and 24-hydroxylated D3 enhance human osteoblast differentiation and mineralization. J Cell Biochem, 99: 922-935, 2006.
2006-08 一宮慎吾，小島隆．胸腺ストローマをつなぐタイト結合．奥村康，平野俊夫，佐藤昇志． Annual Review 2006 免疫，中外医学社．151-156，2005．
2006-09 Fujita H, Chiba H, Yokozaki H, Sakai N, Sugimoto K, Wada T, Kojima T, Yamashita T, Sawada N. Differential expression and subcellular localization of claudin-7, -8, -12, -13, and -15 along the mouse intestine. J Histochem Cytochem, 54: 933-944, 2006.
2006-10 Jansen JH, Jahr H, Verhaar JAN, Pols HAP, Chiba H, Weinans H, van Leeuwen JPTM. Stretch-induced modulation of matrix metalloproteinases in mineralizing osteoblasts via extracellular signal-regulated kinase-1/2. J Orthop Res, 24: 1480-1488, 2006.
2006-11 van Driel M, Koedam M, Buuman CJ, Hewison M, Chiba H, Uitterlinden AG, Pols HAP, van Leeuwen JPTM. Evidence for auto/paracrine actions of vitamin D in bone: 1-hydroxylase expression and activity in human bone cells. FASEB J, 20: 2417-2419, 2006.
2006-12 小島隆，今村将史，孫誠一，村田雅樹，平田公一，澤田典均．黄疸とタイト結合蛋白claudin． Surgery Frontier 13 (2) 80-84, 2006．
2006-13 Osanai M, Murata M, Nishikiori N, Chiba H, Kojima T, Sawada N. Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes. Cancer Res, 66: 9125-9133, 2006.
2006-14 Go M, Kojima T, Takano K, Murata M, Koizumi J, Kurose M, Kamekura R, Osanai M, Chiba H, Spray D, Himi T, Sawada N. Connexin 26 expression prevents down-regulation of barrier and fence functions of tight junctions by Na+/K+-ATPase inhibitor ouabain in human airway epithelial cell line Calu-3. Exp Cell Res, 312: 3847-3856, 2006.
2006-15 徳永祐一. ヒト大腸高分化腺癌細胞株T84におけるタイト結合蛋白occludinの発現の変化とcarcinoembryonic antigen (CEA)およびCD26 (DPP-IV)の局在. 札幌医学雑誌, 75: T31-T40, 2006.
2006-16 Ichimiya S, Kojima T. Cellular networks of human tymic medullary dtromas coordinated by p53-related transcription factors. J Histochem Cytochem, 54: 1277-1289, 2006.
2006-17 Chiba H, Sakai N, Murata M, Osanai M, Ninomiya T, Kojima T, Sawada N. The nuclear receptor hepatocyte nuclear factor 4alpha acts as a morphogen to induce the formation of microvilli. J Cell Biol, 175: 971-980, 2006.
2000-2005
2000-01 森 道夫，澤田典均．病理医のための細胞小器官［1］ライソソーム．病理と臨床，18(4): 379¬384, 2000.
2000-02 森 道夫，澤田典均．病理医のための細胞小器官［2］ペルオキシソーム．病理と臨床，18(5): 467-470, 2000.
2000-03 澤田典均，高桑麗子，森 道夫．培養細胞とエピトープ・タッギング法．病理と臨床（臨時増刊号），18: 222-223, 2000.
2000-04 Takakuwa R, Kokai Y, Kojima T, Akatsuka T, Tobioka H, Sawada N, Mori, M. Uncoupling of gate and fence functions of MDCK cells by the actin¬depolymerizing reagent mycalolide B. Exp Cell Res, 257: 238-244, 2000.
2000-05 森 道夫, 澤田典均．生命科学の展開と組織細胞化学．第25回組織細胞化学講習会「組織細胞化学2000」, 日本組織細胞化学学会 編集, 学際企画, 9-13, 2000.
2000-06 Utsumi H, Chiba H, Kamimura Y, Osanai M, Igarashi Y, Tobioka H, Mori M, Sawada N. Expression of GFRa-1, receptor for GDNF, in rat brain capillary during postnatal development of the BBB. Am J Physiol Cell Physiol, 279: C361-C368, 2000.
2000-07 五十嵐陽．ラット網膜におけるGDNFとNTN：内側血液網膜関門の制御機構における役割．札幌医学雑誌, 69: T11-T18, 2000.
2000-08 Kawaguchi T, Sakisaka S, Mitsuyama K, Harada M, Koga H, Taniguchi E, Sasatomi K, Kimura R, Ueno T, Sawada N, Mori M, Sata M. Cholestasis with altered structure and function of hepatocyte tight junction and decreased expression of canalicular multuspecific organic anion transporter in a rat molel of colitis. Hepatology, 31: 1285-1295, 2000.
2000-09 小海康夫，桑原和英，森 道夫．タイト結合と病気．病理と臨床，18: 1227-1231, 2000.
2000-10 澤田典均， 森 道夫． 細胞の構造と病変の基礎知識．日本毒性病理学会編， 毒性病理組織学，11-30, 2000. （別刷なし）
2000-11 澤田典均，高桑康成，森道夫．ゴルジ装置．病理と臨床，1341-1347, 2000.
2000-12 Igarashi Y, Chiba H, Utsumi H, Miyajima M, Ishizaki T, Gotoh T, Kuwahara K, Tobioka H, Satoh M, Mori M, Sawada N. Expression of receptors for glial cell line-derived neurotrophic factor (GDNF) and neurturin in the inner blood-retinal barrier of rats. Cell Struct Funct, 25: 237-241, 2000.
2000-13 Chiba H, Chambon P, Metzger D. F9 embryonal carcinoma cells engineered for tamoxifen-dependent Cre-mediated site-directed mutagenesis and doxycycline-inducible gene expression. Exp Cell Res, 260: 334-339, 2000.
2001-01 伊藤秀樹，佐藤昌明，武藤省吾，小海康夫，澤田典均．アミロイドの蛍光による観察法．病理と臨床，19: 94-95，2001.
2001-02 Kubota H, Chiba H, Takakuwa Y, Osanai M, Tobioka H, Kohama G, Mori M, Sawada N. Retinoid X receptor alpha and retinoic receptor alpha mediate expression of genes encoding tight-junction proteins and barrier function in F9 cells during visceral endodermal differentiation. Exp Cell Res, 263: 163-172, 2001.
2001-03 Kojima T, Kokai Y, Chiba H, Yamamoto M, Mochizuki Y, Sawada N. Cx32 but not Cx26 is associated with tight junctions in primary cultures of rat hepatocytes. Exp Cell Res, 263: 193-201, 2001.
2001-04 Li M, Chiba H, Warot X, Messaddeq N, Gerard C, Chambon P, Metzger D. RXR alpha ablation in skin keratinocytes results in alopecia and epidermal alterations. Development, 128: 675-688, 2001.
2001-05 Kojima T, Kokai Y, Chiba H, Osanai M, Kuwahara K, Mori M, Mochizuki Y, Sawada N. Occludin and claudin-1 concentrate in the midbody of immortalized mouse hepatocytes during cell division. J Histochem Cytochem, 49: 333-339, 2001.
2001-06 佐久間裕司，山口 潤，飛岡弘敏，佐藤昌明．子宮頸部癌肉腫の1例．診断病理，18: 64-68，2001. （症例報告）
2001-07 澤田典均，宮嶋秀彰，石崎 努，五十嵐 陽，鈴木純一．血管透過性亢進の細胞学的側面-血管網膜関門と神経栄養因子GDNF-．眼科紀要，52: 100-103, 2001.
2001-08 Isogai E, Kokai Y, Isogai H, Yokota K, Oguma K, Ishihara M, Ohno S. Mucosal infection of Streptococcus sanguis in granulocyte colony-stimulating factor transgenic mice- microbiologic model for Behçet's disease. Behçet's Disease (Dongsik Bang, Eun-so Lee, Sungnack Lee eds) Seoul Korea, 139-142, 2001.
2001-09 Akatsuka T, Wada T, Kokai Y, Yamawaki S, Ishii S. Loss of ErbB2 overexpression in pulmonary metastatic lesion in osteosarcoma. Oncology, 60: 361-366, 2001.
2001-10 Kuwabara H, Kokai Y, Kojima T, Takakuwa R, Mori M, Sawada N. Occludin regulates actin cytoskeleton in endothelial cells. Cell Struct Funct, 26: 109-116, 2001.
2001-11 澤田典均，石崎努．血液脳関門．からだの科学220，92-96，2001.
2001-12 Osanai M, Miyokawa N, Tamaki T, Yonekawa M, Kawamura A, Sawada N. Adenocarcinoma arising in gastric heterotopic pancreas: clinicopathological and immunohistochemical study with genetic analysis of a case. Pathol Internal, 51: 549-554, 2001.
2001-13 Kuwabara H, Wada T, Oda T, Yoshikawa H, Sawada N, Kokai Y, Ishii S. Overexpression of the granulocyte colony-stimulating factor gene impairs bone morphogenetic protein responsibeness in mice. Lab Invest, 81: 1133-1141, 2001.
2001-14 Kojima T, Fort A, Tao M, Yamamoto M, Spray DC. Gap junction expression and cell proliferation in differentiating cultures of Cx43 KO mouse hepatocytes. Am J Physiol Gastrointest Liver Physiol, G1004-G1013, 2001.
2001-15 Kojima T, Sawada N, Duffy HS, Spray DC. Gap and tight junctions in liver: composition, regulation, and function. The Liver: Biology and Pathobiology, Fourth Edition, edited by Arias, IM et al, Lippincott Williams&Wilkins, Philadelphia, pp29-46, 2001.
2001-16 Sakisaka S, Kawaguchi T, Taniguchi E, Harada S, Sasatomi K, Koga H, Harada M, Kimura R, Sata M, Sawada N, Mori M, Todo S, Kurohiji T. Alterations in tight junctions differ between primary biliary cirrhosis and primary sclerosing cholangitis. Hepatology, 33: 1460-1468, 2001.
2001-17 小島隆，澤田典均．慢性肝炎から肝癌へ：その分子生物学的機序．日本臨床，59: 89-94, 2001.
2001-18 Iba K, Chiba H, Yamashita T, Ishii S, Sawada N. Phase-independent inhibition by retinoic acid of mineralization correlated with loss of tetranectin expression in a human osteoblastic cell line. Cell Struct Funct, 26: 227-233, 2001.
2001-19 Kojima T, Srinivas M, Fort A, Urban M, Lee G-H, Sawada N, Spray DC. Growth-suppressive function of human connexin32 in a conditional immortalized mouse hepatocyte cell line. In Vitro Cell Dev Biol, 37: 589-598, 2001.
2001-20 Yagihashi S, Yamagishi S, Wada R, Baba M, Hohman TC, Yabe-Nishimura C, Kokai Y. Neuropathy in diabetic mice overexpressing human aldose reductase and effects of aldose reductase inhibitor. Brain, 124: 2448-2458, 2001.
2001-21 Ryushi S, Yasuyuki Y, Reiko T, Shinobu S, Hiroshi U, Hiroto Y, Kenji S, Kiyotaka Y, Hirotsugu T, Yasuhiro U. Atypical angiodysplasia with varicose appearance. Gastrointestinal Endoscopy, 5: 640-642, 2001.
2001-22 Oguro K, Jover T, Tanaka H, Lin Y, Kojima T, Oguro N, Grooms SY, Bennett MVL, Zukin RS. Global Ischemia-Induced Increases in the Gap Junctional Proteins Connexin 32 (Cx32) and Cx36 in Hippocampus and Enhanced Vulnerability of Cx32 Knock-Out Mice. The Journal of Neuroscience, 21(19): 7534-7542, 2001.
2001-23 Osanai M, Igarashi T, Yoshida Y. Unique cellular features in atypical adenomatous hyperplasia of the lung: ultrastructural evidence of its cytodifferentiation. Ultrastruct Pathol, 25: 367-373, 2001.
2002-01 Suzuki K, Kokai Y, Sawada N, Takakuwa R, Kuwahara K, Isogai H, Mori M. SSI Helicobacter pylorus disrupts the paracellular barrier of the gastric mucosa and lends to neutrophilic gastritis in mice. Virchows Archiv, 440: 318-324, 2002.
2002-02 Takakuwa Y, Kokai Y, Sasaki K, Chiba H, Tobioka H, Mori M, Sawada N. Bile canalicular barrier function and expression of tight junctional molecules in rat hepatocytes during common bile duct ligation. Cell Tissue Res, 307: 181-189, 2002.
2002-03 Akatsuka T, Wada T, Kokai Y, Isu K, Kawaguchi S, Yamashiro K, Yamashita T, Sawada N, Yamawaki S, Ishii S. ErbB2 expression is correlated with increased survival of patients with osteosarcoma. Cancer, 94: 1397-1404, 2002.
2002-04 Tobioka H, Isomura H, Kokai Y, Sawada N. Polarised distribution of carcinoembryonic antigen is associated with a tight junction in human colorectal adenocarcinomas. J Pathol, 198: 207-212, 2002
2002-05 Kojima T, Spray DC, Kokai Y, Chiba H, Mochizuki Y, Sawada N. Cx32 formation and/or Cx32-mediated intercellular communication induce expression and function of tight junctions in hepatocytic cell line. Exp Cell Res, 276: 40-51, 2002.
2002-06 Osanai M, Chiba H, Kojima T, Fujibe M, Kimura H, Satoh M, Sawada N. Hepatocyte nuclear factor (HNF)-4 alpha induces expression of endothelial Fas ligand (FasL) to prevent cancer cell transmigration: A novel defense mechanism of endothelium against cancer metastasis. Jpn J Cancer Res, 93: 532-541, 2002
2002-07 Sasaki Y, Ishida S, Morimoto I, Yamashita T, Kojima T, Kihara C, Tanaka T, Imai K, Nakamura Y, Tokino T. The p53 family member genes are involved in the Notch signal pathway. J Biol Chem, 4: 719-724, 2002.
2002-08 Kokai Y, Wada T, Oda T, Kuwabara H, Hara K, Akiyama Y, Ishi S, Sawada, N. Overexpression of Granulocyte colony-stimulating Factor Induces Severe Osteopenia in Developing Mice That K2 (Menatetrenone), Bone, 30: 880-885, 2002.
2002-09 Miyahara T, Simoura T, Osahune N, Uchida Y, Sakuma T, Nemoto N, Kozakai A, Takamura T, Yamazaki R, Higuchi S, Chiba H, Iba K, Sawada N. A highly potent 26,27-hexafluoro-1alpha,25-dihydroxyvitamin D3 on calcification in SV40-transformed human fetal osteoblastic cells. Calcif Tissue Int , 70: 488-495, 2002.
2002-10 Kamimura Y, Chiba H, Utsumi H, Gotoh T, Tobioka H, Sawada N. Barrier function of microvessels and roles of glial cell line-derived neurotrophic factor in the rat testis. Med Electron Microsc, 35: 139-145, 2002.
2002-11 Kimura S, Kawaguchi S, Wada T, Nagoya S, Yamashita T, Kikuchi K. Rhabdomyosarcoma Arising From a Dormant Dumbbell Ganglioneuroma of the Lumbar Spine. Lippincott Williams & Wilkins, 23: 513-517, 2002.
2002-12 宮嶋秀彰. 各種のAGEによるグリア細胞におけるGDNF発現の変化に関する検討. 札幌医学雑誌, 71: T51-T58, 2002.
2002-13 前島澄子, 保谷俊行, 佐藤正幸, 高橋秀史, 高岡和夫, 飛岡弘敏, 服部淳夫, 井上勝一, 秦温信. 迅速hematoxylin-eosin染色による甲状腺捺印細胞診の検討. 日本臨床細胞学会北海道支部会報, 第11巻別刷.
2002-14 Ichimiya S, Kojima T, Momota H, Kondo N, Ozaki T, Nakagawara A, Toribio M L, Imamura M, Sato N. p73 is expressed in human thymic epithelial cells. J Histochem Cytochem, 50: 455-462, 2002.
2002-15 Osanai M, Tamaki T, Yonekawa M, Kawamura A, Sawada N. Transient increase in telomerase activity of proliferating fibroblasts and endothelial cells in granulation tissue of the human skin. Wound Repair Regen, 10: 59-66, 2002.
2003-01 Chiba H, Gotoh T, Kojima T, Satohisa S, Kikuchi K, Osanai M, Sawada N. Hepatocyte nuclear factor (HNF)-4alpha triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells. Exp Cell Res, 286: 288-297, 2003.
2003-02 澤田典均, 小島隆, 飛岡弘敏, 小海康夫, 千葉英樹. “すきま”の細胞生物学―細胞間接着装置タイト結合とヒト疾患―. 札幌医学雑誌, 72: 1-7, 2003.
2003-03 Thi MM, Kojima T, Cowin SC, Weinbaum S, Spray DC. Fluid shear stress remodels expression and function of junctional proteins in cultured bone cells. Am J Physiol Cell Physiol, 284: C389-C403, 2003.
2003-04 Ishizaki T, Chiba H, Kojima T, Fujibe M, Soma T, Miyajima H, Nagasawa K, Wada I, Sawada N. Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways. Exp Cell Res, 290: 275-288, 2003.
2003-05 Sawada N, Murata M, Kikuchi K, Osanai M, Tobioka H, Kojima T, Chiba H. Tight junctions and human diseases. Med Electron Microsc, 36: 147-156, 2003.
2003-06 伊藤泰成. Hepatocyte nuclear factor (HNF) –4alphaによるp21waf1/cip1の発現誘導と細胞増殖の抑制. 札幌医学雑誌, 72: T55-62, 2003.
2003-07 Kojima T, Yamamoto T, Murata M, Chiba H, Kokai Y, Sawada N. Regulation of the blood-biliary barrier: interaction between gap and tight junctions in hepatocytes. Med Electron Microsc, 36: 157-164, 2003.
2003-08 Kojima T, Yamamoto T, Murata M, Lan M, Takano K, Go M, Ichimiya S, Chiba H, Sawada N. Role of the p38 MAP-kinase signaling pathway for Cx32 and claudin-1 in the rat liver. Cell Commun Adhes, 10(4-6): 437-443, 2003.
2003-09 Satoh A, Toyota M, Itoh F, Sasaki Y, Suzuki H, Ogi K, Kikuchi T, Mita H, Yamashita T, Kojima T, Kusano M, Fujita M, Hosokawa M, Endo T, Tokino T, Imai K. Epigenetic Inactivation of CHFR and Sensitivity to microtubule inhibitors in gastric cancer. Cancer Res, 63: 8606-8613, 2003.
2004-01 Fujibe M, Chiba H, Kojima T, Soma T, Wada T, Yamashita T, Sawada N. Thr203 of claudin-1, a putative phosphorylation site for MAP kinase, is required to promote the barrier function of tight junctions. Exp Cell Res, 295: 36-47, 2004.
2004-02 Tobioka H, Isomura H, Kokai Y, Tokunaga Y, Yamaguchi J, Sawada N. Occludin expression decreases with the progression of human endometrial carcinoma. Hum Pathol, 35: 159-164, 2004.
2004-03 Kikuchi T, Ichimiya S, Kojima T, Crisa L, Kondo N, van der Saag PT, Yokoyama S, Sato N. Expression profiles and functional implications of p53-like transcription factors in thymic epithelial cell subtypes. Int Immunol, 16: 831-841, 2004.
2004-04 Kojima T, Yamamoto T, Lan M, Murata M, Takano K, Go M, Ichimiya S, Chiba H, Sawada N. Inhibition of MAP-kinase activity moderates changes in expression and function of Cx32 but not claudin-1 during DNA synthesis in primary cultures of rat hepatocytes. Med Electron Microsc, 37: 101-113, 2004.
2004-05 千葉英樹, 藤田裕樹, 長澤邦彦, 澤田典均. 血液組織関門の形成と制御の分子機構. 福岡医誌, 95: 139-145, 2004.
2004-06 村井政史, 水越常徳, 石田禎夫, 鶴間哲弘, 千葉英樹, 丸山怜緒, 高橋文彦, 伊藤嘉行, 安達正晃, 今井浩三. 腹部転移巣において未分化転化を認めた甲状腺乳頭癌の1部検例. 癌の臨床, 50: 405-409, 2004.
2004-07 小島隆, 村田雅樹, 澤田典均. ギャップ結合とタイト結合―形態学的関係から機能的関係へ-. 顕微鏡, 39: 110-115, 2004.
2004-08 Tokunaga Y, Tobioka H, Isomura H, Kokai Y, Sawada N. Expression of occludin in human rectal carcinoid tumours as a possible marker for glandular differentiation. Histopathology, 44: 247-250, 2004.
2004-09 Jansen JHW, Weyts FAA, Westbroek I, Jahr H, Chiba H, Pols HAP, Verhaar JAN, Leeuwen van JPTM, and Weinans H. Stretch-induced phosphorylation of ERK1/2 depends on differentiation stage of osteoblasts. J Cell Biochem, 93: 542-551, 2004.
2004-10 Yamamoto T, Kojima T, Murata M, Takano K, Go M, Chiba H, Sawada N. IL-1beta regulates expression of Cx32, occludin, and claudin-2 of rat hepatocytes via distinct signal transduction pathways. Exp Cell Res, 299: 427-441, 2004.
2004-11 Soma T, Chiba H, Kato-Mori Y, Wada T, Yamashita T, Kojima T, Sawada N. Thr207 of claudin-5 is involved in size-selective loosening of the endothelial barrier by cyclic AMP. Exp Cell Res, 300: 202-212, 2004.
2004-12 Osanai M, Yamaguchi J, Kikuchi K, Satoh M, Sawada N. Unique cellular features of peripheral primitive neuroectodermal tumor: ultrastructural evidence of its unique cytodifferentiation. Med Electron Microsc, 37: 193-197, 2004.
2004-13 Lan MD, Kojima T, Osanai M, Chiba H, Sawada N. Oncogenic raf-1 regulates epithelial to mesenchymal transition via distinct signal transduction pathways in an immortalized mouse hepatic cell line. Carcinogenesis, 25: 2385-2395, 2004.
2004-14 Nakanishi K, Kamiguchi K, Torigoe T, Nabeta C, Hirohashi Y, Asanuma H, Tobioka H, Koge N, Harada O, Tamura Y, Nagano H, Yano S, Chiba S, Matsumoto H, Sato N. Localization and function in endoplasmic reticulum stress tolerance of ERdj3, a new member of Hsp40 family protein. Cell Stress & Chaperones, 9: 253-264, 2004.
2004-15 Go M, Kojima T, Takano K, Murata M, Ichimiya S, Tsubota H, Himi T, Sawada N. Expression and function of tight junctions in the crypt epithelium of human palatine tonsils. J Histochem Cytochem, 52: 1627-1638, 2004.
2004-16 Tobioka H, Tokunaga Y, Isomura H, Kokai Y, Yamaguchi J, Sawada N. Expression of occludin, a tight-junction-associated protein, in human lung carcinomas. Virchows Archiv, 445: 472-476, 2004.
2004-17 郷充. ヒト気管支上皮細胞株Calu-3をモデルとしたconnexin 26による内耳機能調節のメカニズム解析. 札幌医学雑誌, 73: T25-T33, 2004.
2004-18 Osanai M, Yamaguchi J, Kikuchi K, Murata M, Goto T, Ikeda T, Satoh M, Sawada N, Hirachi K. Vascular transformation of lymph node sinuses. 帯厚医誌, 7: 118-121, 2004.
2005-01 Chiba H, Itoh T, Satohisa S, Sakai N, Osanai M, Kojima T, Sawada N. Activation of p21CIP1/WAF1 gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha. Exp Cell Res, 302: 11-21, 2005.
2005-02 Oda T, Wada T, Kuwabara H, Sawada N, Yamashita T, Kokai Y. Ovariectomy fails to augment bone resorption and marrow B lymphopoiesis in granulocyte colony-stimulating factor transgenic mice. J Orthop Sci, 10: 70-76, 2005.
2005-03 Murata M, Kojima T, Yamamoto T, Go M, Takano K, Chiba H, Tokino T, Sawada N. Tight junction protein MAGI-1 is up-regulated by transfection with connexin32 in an immortalized mouse hepatic cell line: cDNA microarray analysis. Cell Tissue Res, 319: 341-347, 2005.
2005-04 小島隆，山本敏誠，高野賢一，郷充，畠山尚子，村田雅樹，澤田典均．ギャップ結合の病態解析法，細胞：技術講座，37(7): 42-45, 2005.
2005-05 Odajima T, Sasaki Y, Tanaka N, Kato-Mori Y, Asanuma H, Ikeda T, Satoh M, Hiratsuka H, Tokino T, Sawada N. Abnormal beta-catenin expression in oral cancer with no gene mutation: correlation with expression of cyclin D1 and epidermal growth factor receptor, Ki-67 labeling index, and clinicopathological features. Human Pathology, 36: 234-241, 2005.
2005-06 Takano K, Kojima T, Go M, Murata M, Ichimiya S, Himi T, Sawada N. HLA-DR- and CD11c-positive dendritic cells penetrate beyond well-developed epithelial tight junctions in human nasal mucosa of allergic rhinitis. J Histochem Cytochem, 53(5): 611-619, 2005.
2005-07 Miyajima H, Osanai M, Chiba H, Nishikiori N, Kojima T, Ohtsuka K, Sawada N. Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes. Biochem Biophys Res Commun, 330: 361-366, 2005.
2005-08 Yamamoto T, Kojima T, Murata M, Takano K, Go M, Hatakeyama N, Chiba H, Sawada N. p38 MAP-kinase regulates function of gap and tight junctions during regeneration of rat hepatocytes. J Hepatol, 42: 707-718, 2005.
2005-09 Eijken M, Hewison M, Cooper MS, Jong de FH, Chiba H, Stewart PM, Uitterlinden AG, Pols HAP, van Leeuwen JPTM. 11beta-Hydroxysteroid dehydrogenase expression and glucocorticoid synthesis are directed by a molecular switch during osteoblast differentiation. Mol Endocrinol, 19(3): 621-631, 2005.
2005-10 Satohisa S, Chiba H, Osanai M, Ohno S, Kojima T, Saito T, Sawada N. Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization. Exp Cell Res, 310: 66-78, 2005.
2005-11 Murata M, Kojima T, Yamamoto T, Go M, Takano K, Osanai M, Chiba H, Sawada N. Down-regulation of survival signaling through MAPK and Akt in occludin-deficient mouse hepatocytes in vitro. Exp Cell Res, 310: 140-151, 2005. 2005-12 Osanai M, Petkovich M. Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death. Mol Pharmacol, 67: 1808-1817, 2005.
2005-13 Nishikiori N, Mitamura Y, Tashimo A, Nakamura Y, Harada T, Osanai M, Sawada N, Ohtsuka K. Glial cell line-derived neurotrophic factor in the vitreous of patients with proliferative diabetic retinopathy. Diabetes Care, 10: 2588, 2005.