Research
The
human body includes various compartments that maintain considerable
independence from blood by means of a continuous cell sheet. For the
functions of these compartments, passage through the intercellular spaces
of the sheet must be strictly regulated by tight junctions. Once tight
junctions are disturbed, illnesses such as edema, jaundice or diarrhea
will develop. Our department has been trying to expand our understanding
of molecular regulation of tight junctions in regard to treatment of
human diseases.
