Asklepios

北海道公立大学法人
札幌医科大学
医学部附属 フロンティア医学研究所

細胞科学部門

 


 

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2017年

Kaneko Y, Kohno T, Kakuki T, Takano K, Ogasawara N, Miyata R, Kikuchi S, Konno T, Ohkuni T, Kakiuchi A, Yajima R, Yokota S, Himi T, Kojima T.
    Scientific Rep. 2017; 7(1):10935
The role of transcriptional factor p63 in regulation of epithelial barrier and ciliogenesis of human nasal epithelial cells.

Kojima T, Kohno T, Kubo T, Kaneko Y, Kakuki T, Kakiuchi A, Kurose M, Takano KI, Ogasawara N, Obata K, Nomura K, Miyata R, Konno T, Ichimiya S, Himi T.
    Ann. N. Y. Acad. Sci. 2017; 1405(1):25-31.
Regulation of claudin-4 via p63 in human epithelial cells.

Takano K, Kakuki T, Kaneko Y, Kohno T, Kikuchi S, Himi T, Kojima T.
    PLOS ONE. 2017; 12(8):e0182291
Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells

Kikuchi S, Ninomiya T, Kohno T, Kojima T, Tatsumi H.
    Cell Biol. Toxicol. 2017; In press
Cobalt Inhibits Motility of Axonal Mitochondria and Induces Axonal Degeneration in Cultured Dorsal Root Ganglion Cells of Rat

Kohno T, Kikuchi S, Ninomiya T, Kojima T.
    Ann. N. Y. Acad. Sci. 2017; 1397(1):185-194.
The bicellular tensile force sorts the localization of LSRs in bicellular and tricellular junctions.

Shimada H, Abe S, Kohno T, Satohisa S, Konno T, Takahashi S, Hatakeyama T, Arimoto C, Kakuki T, Kaneko Y, Takano K, Saito T, Kojima T.
    Scientific Rep. 2017; 7:37049.
Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer.

Yamaguchi M, Hirai S, Tanaka Y, Sumi T, Miyajima M, Mishina T, Yamada G, Otsuka M, Hasegawa T, Kojima T, Niki T, Watanabe A, Takahashi H, Sakuma Y.
    Lab Invest. 2017; 97(3):232-242.
Fibroblastic foci, covered with alveolar epithelia exhibiting epithelial-mesenchymal transition, destroy alveolar septa by disrupting blood flow in idiopathic pulmonary fibrosis.




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2016年

Takano K, Kakuki T, Obata K, Nomura K, Miyata R, Kondo A, Kurose M, Kakiuch A, Kaneko Y, Kohno T, Himi T, Kojima T.
    Anticancer Research 2016; 36(11):5895-5904.
The behavior and role of lipolysis-stimulated lipoprotein receptor, a component of tricellular tight junctions, in head and neck squamous cell carcinomas.

Masuda T, Taniguchi M.
    Cell Adh Migr. 2016; 10(6):593-603.
Contribution of semaphorins to the formation of the peripheral nervous system in higher vertebrates.

Takasawa A, Murata M, Takasawa K, Ono Y, Osanai M, Tanaka S, Nojima M, Kono T, Hirata K, Kojima T, Sawada N.
    Scientific Rep. 2016; 6:33582.
Nuclear localization of tricellulin promotes the oncogenic property of pancreatic cancer.

Hashimoto S, Yamamoto S, Ogasawara N, Sato T, Yamamoto K, Katoh H, Kubota T, Shiraishi T, Kojima T, Himi T, Tsutsumi H, Yokota S.
    PLOS ONE. 2016; 11(8):e0161793.
Mumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.

Yamamoto K, Yamamoto S, Ogasawara N, Takano K, Shiraishi T, Sato T, Miyata R, Kakuki T, Kamekura R, Kojima T, Tsutsumi H, Himi T, Yokota S.
    Pharmacol Res. 2016; 111:804-14.
Clarithromycin prevents human respiratory syncytial virus-induced airway epithelial responses by modulating activation of interferon regulatory factor-3.

Kakuki T, Kaneko Y, Takano K, Ninomiya T, Kohno T, Kojima T, Himi T.
    Adv. Otorhinolaryngol. 2016; 77:27-32.
Behavior of Primary Cilia and Tricellular Tight Junction Proteins during Differentiation in Temperature-Sensitive Mouse Cochlear Precursor Hair Cells.

Kurose M, Kakuki T, Takano K, Kondo A, Obata K, Nomura K, Miyata R, Kaneko Y, Konno T, Kohno T, Kojima T, Himi T.
    Adv. Otorhinolaryngol. 2016; 77:92-97.
Junctional Adhesion Molecule-A in Head and Neck Squamous Cell Carcinoma.

Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, Hatakeyama T, Arimoto C, Saito T, Kojima T
    Oncology Letters 2016; In press
Downregulation of LSR promotes cell invasion via claudin-1-mediated MMPs in human endometrial cancer.

Kojima T, Soyka MB.
    Global Atlas of Allergic Rhinitis and Chronic Rhinosinusitis. EAACI; Section A, chater 19, pp51-53.
The epithelial barrier in the nose.

Shimada H, Satohisa S, Kohno T, Takahashi S, Hatakeyama T, Konno K, Tsujiwaki M, Saito T, Kojima T.
    Oncotarget 2016; 7(19):27735-52.
The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells.

Kakuki T, Kurose M, Takano K, Kondoh A, Obata K, Nomura K, Miyata R, Kaneko Y, Konno T, Takahashi S, Hatakeyama T, Kohno T, Himi T, Kojima T.
    Oncotarget 2016; 7(23):33887-900.
Dysregulation of junctional adhesion molecule-A via p63/GATA-3 in head and neck squamous cell carcinoma.

Abe A, Takano K, Kojima T, Nomura K, Kakuki T, Kaneko Y, Yamamoto M, Takahashi H, Himi T.
    J. Mol. Histol.  2016; 47(3):353-63.
Interferon-gamma increased epithelial barrier function via upregulating claudin-7 expression in human submandibular gland duct epithelium.

Sakuma Y, Nishikiori H, Hirai S, Yamaguchi M, Yamada G, Watanabe A, Hasegawa T, Kojima T, Niki T, Takahashi H.
    Lab Invest. 2016; 96(4):391-8.
Prolyl isomerase Pin1 promotes survival in EGFR-mutant lung adenocarcinoma cells with an epithelial-mesenchymal transition phenotype.

Okita K, Mizuguchi T, Shigenori O, Ishii M, Nishidate T, Ueki T, Meguro M, Kimura Y, Tanimizu N, Ichinohe N, Torigoe T, Kojima T, Mitaka T, Sato N, Sawada N, Hirata K.
    Surg Today. 2016; 46(6):633-40.
Pancreatic regeneration: basic research and gene regulation.




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2015年

Kono T, Kondoh M, Kyuno D, Ito T, Kimura Y, Imamura M, Kohno T, Konno T, Furuhata T, Sawada N, Hirata K, Kojima T.
    Pharmacol. Res. Perspect. 2015; 3(6):e00196.
Claudin-4 binder C-CPE 194 enhances effects of anticancer agents on pancreatic cancer cell lines via a MAPK pathway.

Kojima T, Kondoh M, Keira T, Takano KI, Kakuki T, Kaneko Y, Miyata R, Nomura K, Obata K, Kohno T, Konno T, Sawada N, Himi T.
    Drug Deliv.  2015; 23(8):2703-2710.
Claudin-binder C-CPE mutants enhance permeability of insulin across human nasal epithelial cells.

Miyata R, Kakuki T, Nomura K, Ohkuni T, Ogasawara N, Takano KI, Konno T, Kohno T, Sawada N, Himi T, Kojima T.
    Eur. J. Pharmacol. 2015; 761:375-82.
Poly(I:C) induced microRNA-146a regulates epithelial barrier and secretion of proinflammatory cytokines in human nasal epithelial cells.

Kohno T, Ninomiya T, Kikuchi S, Konno T, Kojima T.
    Mol. Pharmacol. 2015; 87(5):815-24.
Staurosporine Induces Formation of Two Types of Extra-Long Cell Protrusions: Actin-Based Filaments and Microtubule-Based Shafts.
本論文の図が『Molecular Pharmacology』誌 5月号の表紙に採用されました。

Miyata R, Nomura K, Kakuki T, Takano KI, Kohno T, Konno T, Sawada N, Himi T, Kojima T.
    J. Membr. Biol. 2015; 248(2):327-36.
Irsogladine Maleate Regulates Gap Junctional Intercellular Communication-Dependent Epithelial Barrier in Human Nasal Epithelial Cells.

Masuda T, Taniguchi M.
    Congenit Anom (Kyoto). 2015; 55(1):26-30.
Congenital diseases and semaphorin signaling: Overview to date of the evidence linking them.

Konno T, Ninomiya T, Kohno T, Kikuchi S, Sawada N, Kojima T.
    Histochem. Cell Biol. 2015; 143(5):471-9.
c-Jun N-terminal kinase inhibitor SP600125 enhances barrier function and elongation of human pancreatic cancer cell line HPAC in a Ca-switch model.

Tsujiwaki M, Murata M, Takasawa A, Hiratsuka Y, Fukuda R, Sugimoto K, Ono Y, Nojima M, Tanaka S, Hirata K, Kojima T, Sawada N.
    Med. Mol. Morphol. 2015; 48(1):33-43.
Aberrant expression of claudin-4 and -7 in hepatocytes in the cirrhotic human liver.




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2014年

Takano K, Kojima T, Sawada N, Himi T.
    Excli. J. 2014; 13:1145-1162.
Role of tight junctions in signal transduction: an update.

Masuda T, Sakuma C, Yaginuma H, Taniguchi M.
    Cell Adh. Migr.  2014; 8(6):603-6.
Attractive and permissive activities of semaphorin 5A toward dorsal root ganglion axons in higher vertebrate embryos.

Kubo T, Sugimoto K, Kojima T, Sawada N, Sato N, Ichimiya S.
    Biochem. Biophys. Res. Commun. 2014; 455(3-4):205-11.
Tight junction protein claudin-4 is modulated via ΔNp63 in human keratinocytes.

Kubo T, Kamekura R, Kumagai A, Kawata K, Yamashita K, Mitsuhashi Y, Kojima T, Sugimoto K, Yoneta A, Sumikawa Y, Yamashita T, Sato N, Himi T, Ichimiya S.
    PLOS ONE.  2014; 9:e105498.
ΔNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis.

Kyuno D, Yamaguchi H, Ito T, Kono T, Kimura Y, Imamura M, Konno T, Hirata K, Sawada N, Kojima T.
    World J. Gastroenterol. 2014; 20:10813-10824.
Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer.

Shrestha A, Moe K, Luukko K, Taniguchi M, Kettunen P.
    Cell Tissue. Res. 2014; 357(1):15-29.
Sema3A chemorepellant regulates the timing and patterning of dental nerves during development of incisor tooth germ.

Giacobini P, Parkash J, Campagne C, Messina A, Casoni F, Vanacker C, Langlet F, Hobo B, Cagnoni G, Gallet S, Hanchate NK, Mazur D, Taniguchi M, Mazzone M, Verhaagen J, Ciofi P, Bouret SG, Tamagnone L, Prevot V.
    PLOS Biol.  2014; 12(3):e1001808.
Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A.

Yamashita N, Usui H, Nakamura F, Chen S, Sasaki Y, Hida T, Suto F, Taniguchi M, Takei K, Goshima Y.
    Nat. Commun. 2014; 5, 3424.
Plexin-A4-dependent retrograde semaphorin 3A signalling regulates the dendritic localization of GluA2-containing AMPA receptors.

Nomura K, Obata K, Keira T, Miyata R, Hirakawa S, Takano K, Kohno T, Sawada N, Himi T, Kojima T
    Respir. Res. 2014; 15:21.
Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cells.

Sato T, Kobayashi T, Kuno A, Miki T, Tanno M, Kouzu H, Itoh T, Ishikawa S, Kojima T, Miura T, Tohse N
    Am. J. Physiol. Heart Circ. Physiol. 2014; 306:H1054-H1065.
Type 2 diabetes induces subendocardium-predominant reduction in transient outward K+ current with downregulation of Kv4.2 and KChIP2.




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2013年

Kojima T, Yamaguchi H, Ito T, Kyuno D, Kono T, Konno T, Sawada N.
    Tissue Barriers. 2013; 1(4):e24894
Tight junctions in human pancreatic duct epithelial cells.

Abiko Y, Kojima T, Murata M, Tsujiwaki M, Takeuchi M, Sawada N, Mori M.
    J. Toxicol. Pathol.  2013; 26(4):433-8.
Changes of Tight Junction Protein Claudins in Small Intestine and Kidney Tissues of Mice Fed a DDC Diet.

Kojima T, Ninomiya T, Konno T, Kohno T, Taniguchi M, Sawada N.
    Histol. Histopathol.  2013; 28(11):1383-92.
Expression of tricellulin in epithelial cells and non-epithelial cells.

Obata K, Kojima T, Masaki T, Okabayashi T, Yokota S, Hirakawa S, Nomura K, Takasawa A, Murata M, Tanaka S, Fuchimoto J, Fujii N, Tsutsumi H, Himi T, Sawada N.
    PLOS ONE. 2013; 8(9):e70225.
Curcumin prevents replication of respiratory syncytial virus and the epithelial responses to it in human nasal epithelial cells.

Hirakawa S, Kojima T, Obata K, Okabayashi T, Yokota S, Nomura K, Obonai T, Fuchimoto J, Himi T, Tsutsumi H, Sawada N.
    J. Med. Virol. 2013; 85(12):2141-50.
Marked induction of matrix metalloproteinase-10 by respiratory syncytial virus infection in human nasal epithelial cells.

Masuda T, Taniguchi M, Sakuma C, Yamagishi T, Ueda S, Kawaguchi M, Yaginuma H.
    Congenit Anom (Kyoto).  2013; 53(3):122-6.
Development of the dorsal ramus of the spinal nerve in the mouse embryo: involvement of semaphorin 3A in dorsal muscle innervation.

Someya M, Kojima T, Ogawa M, Ninomiya T, Nomura K, Takasawa A, Murata M, Tanaka S, Saito T, Sawada N.
    Cell Tissue Res.  2013; 354(2):481-94.
Regulation of tight junctions by sex hormones in normal human endometrial epithelial cells and uterus cancer cell line Sawano.

Kojima T, Go M, Takano K, Kurose M, Ohkuni T, Koizumi J, Kamekura R, Ogasawara N, Masaki T, Fuchimoto J, Obata K, Hirakawa S, Nomura K, Keira T, Miyata R, Fujii N, Tsutsumi H, Himi T, Sawada N.
    Biomed. Res. Int.  2013; 947072
Regulation of tight junctions in upper airway epithelium.

Kyuno D, Kojima T, Yamaguchi H, Ito T, Kimura Y, Imamura M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N.
    Carcinogenesis.  2013; 34(6):1232-43.
Protein kinase Cα inhibitor protects against downregulation of claudin-1 during epithelial-mesenchymal transition of pancreatic cancer.

Fuchimoto J, Kojima T, Okabayashi T, Masaki T, Ogasawara N, Obata K, Nomura K, Hirakawa S, Kobayashi N, Shigyo T, Yokota S, Fujii N, Tsutsumi H, Himi T, Sawada N.
    Med. Mol. Morphol. 2013; 46(4):203-9
Humulone suppresses replication of respiratory syncytial virus and release of IL-8 and RANTES in normal human nasal epithelial cells.

Takasawa A, Kojima T, Ninomiya T, Tsujiwaki M, Murata M, Tanaka S, Sawada N.
    Cell Tissue Res.  2013; 351(1):73-84.
Behavior of tricellulin during destruction and formation of tight junctions under various extracellular calcium conditions.




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2012年

Fuchimoto J, Kojima T, Kobayashi N, Ohkuni T, Ogasawara N, Masaki T, Obata K, Nomura K, Kondoh A, Shigyo T, Himi T, Sawada N.
    Am. J. Rhinol. Allergy. 2012; 26(6):433-8.
Hop water extract inhibits double-stranded RNA-induced thymic stromal lymphopoietin release from human nasal epithelial cells.

Moe K, Sijaona A, Shrestha A, Kettunen P, Taniguchi M, Luukko K.
    Differentiation. 2012; 84(5):371-9.
Semaphorin 3A controls timing and patterning of the dental pulp innervation.

Masuda T, Sakuma C, Taniguchi M, Kanemoto A, Yoshizawa M, Satomi K, Tanaka H, Takeuchi K, Ueda S, Yaginuma H, Shiga T.
    Brain Res.  2012; 1480:30-40.
Development of the dorsal ramus of the spinal nerve in the chick embryo: a close relationship between development and expression of guidance cues.

Kojima T, Kyuno D, Sawada N.
    Expert. Opin. Ther. Targets.  2012; 16(9):881-7.
Targeting claudin-4 in human pancreatic cancer.

Kojima T, Sawada N.
    Ann. N. Y. Acad. Sci. 2012; 1257:85-92.
Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells.

Ogawa M, Kojima T, Someya M, Nomura K, Takasawa A, Murata M, Tanaka S, Saito T, Sawada N.
    Histochem. Cell Biol. 2012; 138(2):323-38.
Epidermal growth factor modulates claudins and tight junctional functions in ovarian cancer cell lines.

Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H.
    Nature. 2012; 485(7396):69-74.
Osteoprotection by semaphorin 3A.

Ara S, Kikuchi T, Matsumiya H, Kojima T, Kubo T, Ye RC, Sato A, Kon S, Honma T, Asakura K, Hasegawa T, Himi T, Sato N, Ichimiya S.
    Cancer Sci.  2012; 103(7):1356-62
Sorting nexin 5 of a new diagnostic marker of papillary thyroid carcinoma regulates Caspase-2.

Nomura K, Kojima T, Fuchimoto J, Obata K, Keira T, Himi T, Sawada N.
    Laryngoscope. 2012; 122(6):1185-92.
Regulation of interleukin-33 and thymic stromal lymphopoietin in human nasal fibroblasts by proinflammatory cytokines.

Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T.
    Clin. Exp. Allergy. 2012; 42(2):218-28.
The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis.

Maeda T, Murata M, Chiba H, Takasawa A, Tanaka S, Kojima T, Masumori N, Tsukamoto T, Sawada N.
    Prostate. 2012; 72(4):351-60.
Claudin-4-targeted therapy using Clostridium perfringens enterotoxin for prostate cancer.




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2011年

Kyuno D, Kojima T, Ito T, Yamaguchi H, Tsujiwaki M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N.
    Cell Tissue Res.  2011; 346(3):369-81.
Protein kinase Cα inhibitor enhances the sensitivity of human pancreatic cancer HPAC cells to Clostridium perfringens enterotoxin via claudin-4.

Tsutsumi H, Kojima T, Hirakawa S, Masaki T, Okabayashi T, Yokota S, Fujii N, Himi T, Sawada N.
    Adv. Otorhinolaryngol. 2011; 72:153-6.
Respiratory syncytial virus infection and the tight junctions of nasal epithelial cells.

Himi T, Takano K, Ogasawara N, Go M, Kurose M, Koizumi J, Kamekura R, Kondo A, Ohkuni T, Masaki T, Kojima T, Sawada N, Tsutsumi H.
    Adv. Otorhinolaryngol. 2011; 72:28-30.
Mucosal immune barrier and antigen-presenting system in human nasal epithelial cells.

Ariki S, Kojima T, Gasa S, Saito A, Nishitani C, Takahashi M, Shimizu T, Kurimura Y, Sawada N, Fujii N, Kuroki Y.
    J. Immunol. 2011; 187(5):2586-94.
Pulmonary collectins play distinct roles in host defense against Mycobacterium avium.

Okabayashi T, Kojima T, Masaki T, Yokota S, Imaizumi T, Tsutsumi H, Himi T, Fujii N, Sawada N.
    Virus. Res. 2011; 160(1-2):360-6.
Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells.

Kojima T, Takasawa A, Kyuno D, Ito T, Yamaguchi H, Hirata K, Tsujiwaki M, Murata M, Tanaka S, Sawada N.
    Exp. Cell Res. 2011; 317(16):2288-98.
Downregulation of tight junction-associated MARVEL protein marvelD3 during epithelial-mesenchymal transition in human pancreatic cancer cells.

Kojima T, Sawada N.
    Methods Mol. Biol. 2011; 762:233-44.
Expression and function of claudins in hepatocytes.

Maeda T, Murata M, Chiba H, Takasawa A, Tanaka S, Kojima T, Masumori N, Tsukamoto T, Sawada N.
    Prostate. 2011; 72(4):351-60.
Claudin-4-targeted therapy using Clostridium perfringens enterotoxin for prostate cancer.

Kabayama H, Takeuchi M, Taniguchi M, Tokushige N, Kozaki S, Mizutani A, Nakamura T, Mikoshiba K.
    J. Neurosci. 2011; 31(20):7357-64.
Syntaxin 1B suppresses macropinocytosis and semaphorin 3A-induced growth cone collapse.

Yamaguchi H, Kojima T, Ito T, Kyuno D, Kimura Y, Imamura M, Hirata K, Sawada N.
    Cell Mol. Biol. Lett. 2011; 16(3):385-97.
Effects of Clostridium perfringens enterotoxin via claudin-4 on normal human pancreatic duct epithelial cells and cancer cells.

Masaki T, Kojima T, Okabayashi T, Ogasawara N, Ohkuni T, Obata K, Takasawa A, Murata M, Tanaka S, Hirakawa S, Fuchimoto J, Ninomiya T, Fujii N, Tsutsumi H, Himi T, Sawada N.
    Mol. Biol. Cell.  2011; 22(13):2144-56.
A nuclear factor-κB signaling pathway via protein kinase C δ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells.

Kondoh A, Takano K, Kojima T, Ohkuni T, Kamekura R, Ogasawara N, Go M, Sawada N, Himi T.
    Acta Otolaryngol. 2011; 131(8):861-8
Altered expression of claudin-1, claudin-7, and tricellulin regardless of human papilloma virus infection in human tonsillar squamous cell carcinoma.

Ito T, Kojima T, Yamaguchi H, Kyuno D, Kimura Y, Imamura M, Takasawa A, Murata M, Tanaka S, Hirata K, Sawada N.
    J. Cell Biochem. 2011; 112(7):1761-72.
Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells.

Katsumi A, Kiyoi H, Abe A, Tanizaki R, Iwasaki T, Kobayashi M, Matsushita T, Kaibuchi K, Senga T, Kojima T, Kohno T, Hamaguchi M, Naoe T.
    Eur. J. Haematol. 2011; 86(3):191-8.
FLT3/ ITD regulates leukaemia cell adhesion through α4β1 integrin and Pyk2 signalling.

Taniguchi M, Masuda T, Mikami Y, Kimura M, Yoshida T, Mishina M, Shimizu T.
    Neurosci. Lett. 2011; 488(2):215-20.
Identification and characterization of a novel zebrafish semaphorin.

Ogasawara N, Kojima T, Go M, Takano K, Kamekura R, Ohkuni T, Koizumi J, Masaki T, Fuchimoto J, Obata K, Kurose M, Shintani T, Sawada N, Himi T.
    Acta Otolaryngol. 2011; 131(2):116-23.
Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids.

Ohkuni T, Kojima T, Ogasawara N, Masaki T, Fuchimoto J, Kamekura R, Koizumi J, Ichimiya S, Murata M, Tanaka S, Himi T, Sawada N.
    Toxicol. Appl. Pharmacol. 2011; 250(1):29-38.
Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.




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2010年

Kikuchi S, Ninomiya T, Kawamata T, Ogasawara N, Kojima T, Tachi N, Tatsumi H.
    Arch Histol Cytol. 2010; 73(2):81-9.
The acid-sensing ion channel 2 (ASIC2) of ciliated cells in the developing rat nasal septum.

Kikuchi S, Ninomiya T, Tatsumi H, Sawada N, Kojima T.
    J Histochem Cytochem. 2010; 58(12):1067-73.
Tricellulin is expressed in autotypic tight junctions of peripheral myelinating Schwann cells.

Ogasawara N, Kojima T, Go M, Takano K, Kamekura R, Ohkuni T, Koizumi J, Masaki T, Fuchimoto J, Obata K, Kurose M, Shintani T, Sawada N, Himi T.
    Acta Otolaryngol. 2010; 131(2):116-23.
Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids.

Ohkuni T, Kojima T, Ogasawara N, Masaki T, Fuchimoto J, Kamekura R, Koizumi J, Ichimiya S, Murata M, Tanaka S, Himi T, Sawada N.
    Toxicol Appl Pharmacol. 2010; 250(1):29-38.
Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.

Yamaguchi H, Kojima T, Ito T, Kimura Y, Imamura M, Son S, Koizumi J, Murata M, Nagayama M, Nobuoka T, Tanaka S, Hirata K, Sawada N.
    Am J Pathol.  2010; 177(2):698-712.
Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells.

Kojima T, Fuchimoto J, Yamaguchi H, Ito T, Takasawa A, Ninomiya T, Kikuchi S, Ogasawara N, Ohkuni T, Masaki T, Hirata K, Himi T, Sawada N.
    J Cell Physiol. 2010; 225(3):720-33.
c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells.

Takamatsu H, Takegahara N, Nakagawa Y, Tomura M, Taniguchi M, Friedel RH, Rayburn H, Tessier-Lavigne M, Yoshida Y, Okuno T, Mizui M, Kang S, Nojima S, Tsujimura T, Nakatsuji Y, Katayama I, Toyofuku T, Kikutani H, Kumanogoh A.
    Nat Immunol. 2010; 11(7):594-600.
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II.

Ogasawara N, Kojima T, Go M, Ohkuni T, Koizumi J, Kamekura R, Masaki T, Murata M, Tanaka S, Fuchimoto J, Himi T, Sawada N.
    Pharmacol Res. 2010; 61(6):489-98.
PPARgamma agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells.

Kamekura R, Kojima T, Takashima A, Koizumi J, Ogasawara N, Go M, Takano K, Murata M, Tanaka S, Ichimiya S, Himi T, Sawada N.
    Histochem Cell Biol. 2010; 133(3):339-48.
Thymic stromal lymphopoietin induces tight junction protein claudin-7 via NF-kappaB in dendritic cells.

Sawada K, Ariki S, Kojima T, Saito A, Yamazoe M, Nishitani C, Shimizu T, Takahashi M, Mitsuzawa H, Yokota S, Sawada N, Fujii N, Takahashi H, Kuroki Y.
    J Biol Chem. 2010; 285(11):8434-43.
Pulmonary collectins protect macrophages against pore-forming activity of Legionella pneumophila and suppress its intracellular growth.




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2009年

Ohkuni T, Kojima T, Ogasawara N, Masaki T, Ninomiya T, Kikuchi S, Go M, Takano K, Himi T, Sawada N.
    Med Mol Morphol.  2009; 42(4):204-11.
Expression and localization of tricellulin in human nasal epithelial cells in vivo and in vitro.

Kamekura R, Kojima T, Koizumi J, Ogasawara N, Kurose M, Go M, Harimaya A, Murata M, Tanaka S, Chiba H, Himi T, Sawada N.
    Cell Tissue Res. 2009; 338(2):283-93.
Thymic stromal lymphopoietin enhances tight-junction barrier function of human nasal epithelial cells.

Kojima T, Murata M, Yamamoto T, Lan M, Imamura M, Son S, Takano K, Yamaguchi H, Ito T, Tanaka S, Chiba H, Hirata K, Sawada N.
    Histol Histopathol.  2009; 24(11):1463-72.
Tight junction proteins and signal transduction pathways in hepatocytes.

Ogasawara N, Kojima T, Go M, Fuchimoto J, Kamekura R, Koizumi J, Ohkuni T, Masaki T, Murata M, Tanaka S, Ichimiya S, Himi T, Sawada N.
    Biochem Biophys Res Commun. 2009; 389(3):543-9.
Induction of JAM-A during differentiation of human THP-1 dendritic cells.

Nakamura F, Ugajin K, Yamashita N, Okada T, Uchida Y, Taniguchi M, Ohshima T, Goshima Y.
    J Comp Neurol. 2009; 516(5):360-75.
Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

Iba K, Hatakeyama N, Kojima T, Murata M, Matsumura T, Wewer UM, Wada T, Sawada N, Yamashita T.
    Wound Repair Regen. 2009; 17(1):108-12.
Impaired cutaneous wound healing in mice lacking tetranectin.

Son S, Kojima T, Decaens C, Yamaguchi H, Ito T, Imamura M, Murata M, Tanaka S, Chiba H, Hirata K, Sawada N.
    Histochem Cell Biol.  2009; 131(3):411-24.
Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells.

Kabayama H, Nakamura T, Takeuchi M, Iwasaki H, Taniguchi M, Tokushige N, Mikoshiba K.
    Mol Cell Neurosci. 2009; 40(1):27-38.
Ca2+ induces macropinocytosis via F-actin depolymerization during growth cone collapse.


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